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The researchers conducted brain scans on 30 volunteers, ages 18 to 23, who had depression in their teen years, and a control group of 23 young adults who never had depression. Many regions of the brains in those with a history of depression were hyper-connected, which means they "communicate" with each other a bit too much. This hyper-connectivity was related to rumination, in which a person constantly thinks about a problem without actively attempting to find a solution. The researchers plan to follow the participants to determine if having hyper-connected brain networks predicts a recurrence of depression. If we can provide prevention and treatment to those people that are most at risk, we might be able to prevent depression, reduce the number of depressive episodes , or reduce their severity.

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